CO2 Total Extract
Botanical name: Fraxinus excelsior
Common name: European Ash
Geographical position: 1400m above sea level
Part of the plant used: Leaf (wild)
Appearance: Dark Brown solid.
Major compounds: Carotol, alpha- cadinol, bicyclogermacrene, alpha- muurolol
Odor: Natural and fresh fragrance
Fraxinus excelsior shows hypoglycemic effect in patients with postprandial hypoglycemia, which was a common popular belief until the study cited here presented clinical evidence to support the claim. On the other hand, it was observed to also induce insulin secretion after glucose injection. 
Another study suggests that Fraxinus excelsior supports glucose homeostasis thus helping regulate the balance of insulin and glucagon as study considers elderly overweight patients. 
It was also observed how the presence of polyphenols, tannins, coumarins and flavonoids endow it with antibacterial and antioxidative properties which could be beneficial in treating conditions related. 
According to 2 sepparate studies, Fraxinus excelsior also showed antiobesity and hypoglicemic effect on obese animals (mice/rats), associated with weight loss in one case , and controlled/ limited weigh gain in the other.  The animal subjects of these studies suffered from metabolic disorders. This suggests that Fraxinus e. benefits could be successfully applicable in human patients too. [4, 5]
Visen, Pradeep & Saraswat, Binduja & Visen, Aastha & Roller, Marc & Bily, Antoine & Mermet, Claire & He, K.L. & Bai, Naisheng & Lemaire, Benoit & Lafay, Sophie & Ibarra, Alvin. (2009). Acute effects of Fraxinus excelsior L. seed extract on postprandial glycemia and insulin secretion on healthy volunteers. Journal of ethnopharmacology. 126. 226-32. 10.1016/j.jep.2009.08.039.
Zulet, Maria & Navas-Carretero, Santiago & Lara, Daniela & Abete, Itziar & Flanagan, John & Issaly, Nicolas & Fança-Berthon, Pascale & Bily, Antoine & Roller, Marc & Alfredo, Martinez. (2014). A Fraxinus excelsior L. seeds/fruits extract benefits glucose homeostasis and adiposity related markers in elderly overweight/obese subjects: A longitudinal, randomized, crossover, double-blind, placebo-controlled nutritional intervention study. Phytomedicine : international journal of phytotherapy and phytopharmacology. 21. 10.1016/j.phymed.2014.04.027.
Amamra, S. & Noureddine, Charef & Arrar, Lekhmici & Belhaddad, Oum & Khennouf, Seddik & Zaim, K. & Baghiani, Abderrahmane. (2018). Phenolic Content, Antioxidant and Antibacterial Effects of Fruit Extracts of Algerian Ash, Fraxinus excelsior. Indian Journal of Pharmaceutical Sciences. 80. 10.4172/pharmaceutical-sciences.1000452.
Ibarra, Alvin & Bai, Naisheng & He, K.L. & Bily, Antoine & Cases, Julien & Roller, Marc & Sang, Shengmin. (2010). Fraxinus excelsior seed extract FraxiPure™ limits weight gains and hyperglycemia in high-fat diet-induced obese mice. Phytomedicine : international journal of phytotherapy and phytopharmacology. 18. 479-85. 10.1016/j.phymed.2010.09.010.
 Montó, Fermí & Arce, Cristina & Noguera, Maria & Ivorra, Maria & Flanagan, John & Roller, Marc & Issaly, Nicolas & D'Ocon, Pilar. (2014). Action of an extract from the seeds of Fraxinus excelsior L. on metabolic disorders in hypertensive and obese animal models. Food & Function. 10.1039/c3fo60539f.
* Please, note that the above statements are summaries of published studies and and investigations as cited at the end of each statement.
These are not results or conclusions drawn for Esencial® Laboratory.
The producer of the end product is responsible for the end product effects and the production technology of their product in compliance with specific regulations that guarantee the Consumer Information Rights and their Health Safety.