Hawthorn berries are rich in many bioactive compounds that vary according to the ripeness of the fruit. Over-ripened fruits are rich in carbohydrates, sugars and Saturated Fatty Acids. Unripe fruits exhibit a higher concentration of antioxidants, phenolics included. Also, unripe fruit extract is richer in Polyunsaturated fatty acids while preserving an optimal Unsaturated to Saturated ratio. These analyses of Hawthorn berries’ bioactive components make it applicable in the Nutraceutical Industry. [1] Natural nutrients found in Hawthorn extract are also of interest in the emerging science of Nanonutraceuticals. [2]

Hawthorn fruit antioxidant activity being proportionate to polyphenolic concentration makes it a natural source of antioxidants and a contributor to cardiovascular diseases treatment. [3]

Hawthorn fruit also show anxiolytic effects as well as the time spent in closed arms in EPM reduced. [4]

Hawthorn fruit extract acted as a protective agent in vivo in male mice against reproductive toxicity caused by Doxorubicin. This way, cytoprotective properties of Hawthorn fruit extract reduce adverse and toxic effects of Doxorubicin as a powerful and controversial anti-malignant medication. Hawthorn fruit extract proves to be a natural male fertility remedy as observed when acting against a chemotherapeutic medication by partially preserving sperm count, levels of testosterone and spermatogenic activities. [5]