Bitter orange extract is concluded to have no unwanted or side effects when administered at therapeutic dosages, making it a safe ingredient to be added in edible formulations for dietary purposes. [1]

Its significant pharmacological effect is observed in “anticancer, antianxiety, antiobesity, antibacterial, antioxidant, pesticidal, and antidiabetic activities.”[1]

Its main health benefits are attributed to the richness in alkaloids such as p-synephrine and in metabolites such as flavonoids. [1]

Orange Blossom/ Neroli also shows marked free radical scavenger activity. It is also rich in other health-contributing compounds such as tannins, phenols, flavonoids, monoterpenes, linalool, polyphenols etc. [2]

Its application is also significant in the biotechnological processes. Since Citrus aurantium is a rich natural source of Proteases, this supports fish hydrolysate production. Evaluated at different pH values to observe degradation variations and patterns, Citrus aurantium Proteases seem to be beneficial in the production of fertilizers. [3]

Orange Blossom also shows bactericidal effects and antioxidative properties that play an important role in the Food Industry and Pharmaceuticals. [4]

Except for its role in the Food Industry or Perfumery due to its pleasant aroma and flavor, Citrus aurantium show antibacterial activity in another study where it was tested against “Escherichia coli, Staphylococcus aureus and Pseudomonas.” [5]