Application:
The whole plant has properties such as tonic, anticonvulsive, energizing and antiseptic.
It is administered for the treatment of intestinal infections, diarrhea, colitis, flatulence, liver disorders and jaundice.
Rosemary also is indicated in the treatment of influenza, colds and wounds in the oral cavity
The herbal extract stimulates the circulatory system as increases blood flow in the vessel. [1]
The pharmacological properties are thought to be based on the enhancement of superoxide and hydroxyl scavenging, inhibition of both lowdensity lipoprotein and oil oxidation, inhibition of haemolysis and hyaluronidase and β- hexosaminidase activities.
In vivo studies using mouse models of Alzheimer's disease and amyotrophic lateral sclerosis have shown that rosmarinic acid significantly alleviates memory impairment associated with amyloid beta protein neurotoxicity and significantly delays disease onset. [2] [3]
The anti-inflammatory effects of RosA along with its immunomodulatory effects may also make it a novel agent for the treatment of auto-immune disorders. [4] These findings suggest that RA has potentially anti-fibrogenic effects and can be a promising candidate for ameliorating liver fibrosis. [5]
Literature:
[1] UNIVERSITY of IOANNINA SCHOOL of HEALTH SCIENCES FACULTY of MEDICINE Department of Pharmacology, Medicinal Herb, Salvia rosmarinus.
[2] Yosuke Shimojo, Kunio Kosaka, Yoshihiro Noda, Takahiko Shimizu, Takuji Shirasawa: Effect of Rosmarinic Acid in Motor Dysfunction and Life Span in a Mouse Model of Familial Amyotrophic Lateral Sclerosis November 2009Journal of Neuroscience Research 88(4):896-904. DOI:10.1002/jnr.22242. SourcePubMed.
[3] Sara Nunes,Ana Raquel Madureira,Débora Campos,Bruno Sarmento,Ana Maria Gomes,Manuela Pintado &Flávio Reis: Therapeutic and nutraceutical potential of rosmarinic acid—Cytoprotective properties and pharmacokinetic profile.
[4] The Effect of Rosmarinic Acid on Immunological and Neurological Systems: A Basic Science and Clinical Review, Vol 4 No 1 (2015)
* Please, note that the above statements are summaries of published studies and and investigations as cited at the end of each statement.
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